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Progress in Quantitative Nuclear Magnetic Resonance Technology in Pharmaceutical Applications(PDF)

南京师范大学学报(工程技术版)[ISSN:1006-6977/CN:61-1281/TN]

Issue:
2014年02期
Page:
8-
Research Field:
Publishing date:

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Title:
Progress in Quantitative Nuclear Magnetic Resonance Technology in Pharmaceutical Applications
Author(s):
Zhang Fenfen1Jiang Menghong2Shen Wenbin3Ding Ya1
(1.Department of Pharmaceutical Analysis,China Pharmaceutical University,Nanjing 210009,China) (2.Shanghai Institute for Food and Drug Control,Shanghai 201203,China) (3.Pharmaceutical Research Institute,China Pharmaceutical University,Nanjing 210009,China)
Keywords:
QNMRdevelopment of new drugquality controlmetabolomics
PACS:
R917
DOI:
-
Abstract:
Due to the advantages of its feasibility,high accuracy,simultaneous qualitative and quantitative analysis,as well as the content determination without its own reference substance,Quantitative Nuclear Magnetic Resonance(QNMR)has been widely used in various pharmaceutical fields including development of new drug,research of pharmaceutical reference substance,quality control,and metabolomics.Nowadays,this technology has been adopted as the standard method by the United States Pharmacopeia,British Pharmacopeia,European Pharmacopeia,Japanese Pharmacopeia,and Chinese Pharmacopeia.This paper reviews the principles,methods and applications of QNMR and predicts its perspectives.

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Last Update: 2014-06-30