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Optimization Extraction of Dicaffeoylquinic Acids from Artemisialavandulaefolia DC.Using Response Surface Methodology(PDF)

南京师范大学学报（工程技术版）[ISSN:1006-6977/CN:61-1281/TN]

Issue:
2015年01期
Page:
73-77
Research Field:
化学工程
Publishing date:

Info

Title:
Optimization Extraction of Dicaffeoylquinic Acids from Artemisialavandulaefolia DC.Using Response Surface Methodology
Author(s):
Qian Yuanyuan1; Chen Yuru1; Yang Fengping1; Ke Xiaohong1; Yan Mang1; Tang Chao2
(1.School of Life Science,Jiangsu Engineering and Technology Research Centre for Microbiology Resource,Jiangsu Key Laboratory for Biodiversityand Biotechnology,Jiangsu Key Laboratory for Microbes and Functional Genomic,Nanjing Normal University,Nanjing 2
Keywords:
Artemisia lavandulaefolia DC.; dicaffeoylquinic acids; extraction; response surface methodology; LC/MS
PACS:
TS202.3
DOI:
-
Abstract:
Response surface methodology is applied to optimize the extraction conditions of diCQAs from Artemisia lavandulaefolia DC. The combined effects of independent variables(ethanol concentration,extraction temperature,extraction time,solid-liquid ratio)are studied and the optimal extraction conditions are as follows:ethanol concentration 72%,extraction temperature 53 ℃,extraction time 102 min,solid-liquid ratio 1:54 g/mL. Under these conditions,the yield of diCQAs is 3.30% and the extraction yield is 91%. The content of diCQAs(3,5-diCQA,4,5-diCQA,1,5-diCQA)are 14.2 mg/g,10.5 mg/g and 8.3 mg/g respectively,which are identified by LC/MS. A.lavandulaefolia DC.is the materials that rich in dicaffeoylquinic acids.

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Last Update: 2015-03-30