[1]李丽,杨锦飞,袁相爱.异香豆素类化合物的合成研究及新进展[J].南京师范大学学报(工程技术版),2005,05(02):064-67.
　LI Li,YANG Jinfei,YUAN Xiangai.Study on Synthesis of Isocoumarins and its Evolution[J].Journal of Nanjing Normal University(Engineering and Technology),2005,05(02):064-67.
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异香豆素类化合物的合成研究及新进展
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南京师范大学学报（工程技术版）[ISSN:1006-6977/CN:61-1281/TN]

卷:
05卷
期数:
2005年02期
页码:
064-67
栏目:
出版日期:
2005-06-30

文章信息/Info

Title:
Study on Synthesis of Isocoumarins and its Evolution
作者:
李丽; 杨锦飞; 袁相爱
南京师范大学化学与环境科学学院, 江苏南京210097
Author(s):
LI Li;  YANG Jinfei;  YUAN Xiangai
School of Chemistry and Environment Science, Nanjing Normal University, Jiangsu Nanjing 210097, China
关键词:
异香豆素;  合成;  生物活性
Keywords:
isocoum arin;  synthes is;  bioactiv ity
分类号:
TQ28
摘要:
介绍了异香豆素类化合物在抗癌和其他药理方面的作用,综述了异香豆素类化合物的合成方法,着重介绍其中的二氢类异香豆素化合物的臭氧氧化法、金属有机合成法、催化氧化法、分子间成环缩合法等合成方法,并进行了比较.对于多取代异香豆素类化合物的合成研究也进行了初步的探讨.最后对异香豆素类化合物在生理和生物活性方面的发展前景提出了展望.
Abstract:
The article introduces the anti-tumo r and o ther pharm aco log ic effec ts o f the isocoum ar ins, rev iews the m ethods of synthesizing isocoum arins, and places an em phasis on introducing and compar ing such m ethods of synthe-sizing syntheticroutes o f d ihydroisocoum arins as ozone ox idation, o rganic m eta l sythes is, cata ly tic ox idation and so on. The article a lso m akes a pre lim inary investigation of the synthesis of po ly subtituedisocoum arin, and finally sug- g ests an expec tation for its prospect in phy sio log ical and bio log ica l activ ity.

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备注/Memo

备注/Memo:
基金项目: 南京师范大学环境友好实验室基金资助项目( 181090H 603) .
作者简介: 李 丽, ( 1979-) , 女, 硕士研究生, 主要从事精细化学品及阻燃剂的合成的学习与研究. E-m ail:babylil i2003@ sina. com. cn
通讯联系人: 杨锦飞( 1956-) , 教授, 主要从事阻燃剂与医药中间体合成的教学与研究. E-m ail:yang jin fei@n jnu. edu. cn
更新日期/Last Update: 2013-04-29